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MOTS-c

MOTS-c

Mitochondrial-derived signaling peptide (16 amino acids) that mimics the effects of exercise at the cellular level. Activates AMPK, improves glucose uptake, and enhances fat metabolism - a key tool in metabolic and longevity research.

€159.99

€199.99

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40mg

1

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Lab Report (COA)

Batch Numberyellow cap
Purity99.13%
Testing LabJanoshik
Test Date3 Nov 2025
Download COA

What is MOTS-c?

MOTS-c is a 16-amino-acid mitochondrial-derived peptide (MDP) discovered in 2015 at USC. Encoded in mitochondrial DNA, it's been called the "mitochondrial exercise signal" - its metabolic effects mirror many exercise adaptations, even without physical activity.

Why It Matters

MOTS-c is nicknamed the "exercise pill peptide." It triggers many of the same metabolic benefits as working out - better fat burning, improved blood sugar, more energy - without the treadmill. Your body naturally makes less of it as you age.

Key Research Areas

  • AMPK activation - master energy sensor activation promotes fat oxidation, glucose uptake, and autophagy
  • Exercise mimetic - improved exercise capacity and metabolic fitness in mouse models without exercise
  • Insulin-independent glucose uptake - skeletal muscle glucose disposal independent of insulin signaling
  • Aging - MOTS-c levels decline with age; supplementation restored metabolic parameters in aged mice
  • Immune function - influences T-cell metabolism and differentiation

Specifications

  • Purity: ≥98% (HPLC verified)
  • Form: Lyophilized powder
  • Storage: 2–8°C, use within 4 weeks
  • CoA: Included

Related: SS-31 | NAD+

For Research Purposes Only.

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