Pinealon
Short-peptide bioregulator (Glu-Asp-Arg, EDR) from the Khavinson programme, studied for gene-expression effects in neuronal tissue and for protection of nerve cells under stress. The brain-focused counterpart to Epitalon in the same cytogen series.
€34.99
€44.99
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Khavinson tripeptide
A three-amino-acid peptide (Glu-Asp-Arg, abbreviated EDR) from the Russian short-peptide bioregulator programme.
Neuro-focused bioregulator
Studied in the context of brain and neuronal tissue, the nerve-cell counterpart to Epitalon's pineal focus.
Gene-expression research
Investigated as a short peptide that interacts with DNA and chromatin and influences transcription, rather than as a classic receptor agonist.
Cell-protection endpoints
Laboratory work examines neuronal cultures under oxidative stress or oxygen deprivation.
Same series as Epitalon
Part of the cytogen/bioregulator series developed at the St. Petersburg Institute of Bioregulation and Gerontology.
Lyophilized powder
Supplied freeze-dried, the standard form used across the published research.
Research areas
What is Pinealon
Pinealon is a synthetic tripeptide made of three amino acids: glutamic acid, aspartic acid and arginine (Glu-Asp-Arg, usually abbreviated EDR). It comes from the short-peptide "bioregulator" programme led by the Russian gerontologist Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology, the same programme that produced Epitalon and Thymalin.
Within that programme each short peptide is matched to a tissue. Epitalon is the pineal peptide and Thymalin the thymus peptide, while Pinealon is studied in the context of brain and neuronal tissue. That is the reason it is usually presented as a companion to Epitalon rather than a replacement for it.
We supply it as a lyophilized (freeze-dried) powder, the same form used across the published research.
How it works
The mechanism proposed for the Khavinson short peptides is different from a classic drug-receptor interaction. These peptides are small enough to enter cells, and according to the programme's research they interact directly with DNA and chromatin and influence which genes are transcribed. Pinealon is therefore studied as a regulator of gene expression in neuronal tissue rather than as a receptor agonist.
The laboratory work concentrates on neuronal cell cultures placed under stress, for example oxidative stress or oxygen deprivation, where the peptide is examined for effects on cell survival and on markers of programmed cell death. Animal work within the programme looks at behavioural and cognitive endpoints.
An honest note on the evidence base: the great majority of this literature comes from the Khavinson group itself and is published largely in Russian-language journals. Independent replication outside that programme is limited. The findings should therefore be read as preliminary rather than established. Pinealon holds no marketing authorisation anywhere and is not an approved medicinal product.
Often studied alongside
Epitalon is the pineal peptide from the same series and the compound Pinealon is most often paired with in longevity research.
The pineal peptide from the same Khavinson series
Tetrapeptide (Ala-Glu-Asp-Gly) that activates telomerase, the enzyme responsible for maintaining telomere length. One of the most studied peptides in longevity research, developed by Prof. Khavinson at the St. Petersburg Institute of Bioregulation.
Thymalin covers the immune side of the same bioregulator programme.
Thymus peptide from the same programme
Thymus-derived immune peptide developed by Prof. Khavinson. Restores T-cell function and thymic activity that naturally decline with age. Over 40 years of clinical use in Russia for immune support and anti-aging research.
For reconstitution, the standard solvent in published protocols is bacteriostatic or sterile water.
Standard solvent for reconstitution
USP-grade sterile water with 0.9% benzyl alcohol (near-neutral, ~pH 6) - the standard solvent for reconstituting lyophilized peptides. Essential accessory for any peptide research. Each vial is sealed and ready to use.
Documentation
Material specification
Purity
Test method
Form
Storage (sealed)
Storage (reconstituted)
CoA
Research use only
This material is sold strictly for in-vitro research and laboratory use. Not intended for human or animal consumption, medical, cosmetic, or household applications. Suitable only for professional laboratory environments.
Storage and stability
- Dry, lyophilized vials keep for months refrigerated, or up to 24 months frozen at -20°C.
- After reconstitution in bacteriostatic water, use within about 30 days at 2 to 8°C, and avoid repeated freeze-thaw.
Frequently Asked Questions
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