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Retatrutide

Retatrutide

First-ever triple-action weight management peptide targeting three receptors at once: GIP, GLP-1, and glucagon. Shown exceptional results in Phase 2 trials - up to 24% weight reduction. The most advanced metabolic peptide available.

€149.99

€179.99

Save 17%

15mg

1

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Lab Report (COA)

Batch NumberBlack Cap
Purity99.81%
Testing LabJanoshik
Test Date23 Jan 2026
Download COA

What is Retatrutide?

Retatrutide (LY3437943) is the first triple-acting peptide targeting GIP, GLP-1, and glucagon receptors simultaneously. The addition of glucagon receptor agonism introduces thermogenesis and enhanced hepatic fat oxidation - a dimension missing from dual agonists.

Why It Matters

Retatrutide (LY3437943) is a novel triple-agonist peptide that simultaneously activates GLP-1, GIP, and glucagon receptors. While current mono- and dual-agonists target 1-2 pathways, Retatrutide engages all three metabolic signaling axes. Phase 2 clinical data reported up to 24% mean body weight reduction - among the highest observed in incretin-based research.

Key Research Areas

  • Weight loss - up to 24% mean body weight reduction in Phase 2 trials (approaching bariatric surgery outcomes)
  • Triple mechanism - appetite suppression (GLP-1) + metabolic enhancement (GIP) + energy expenditure (glucagon)
  • Liver fat - glucagon-driven hepatic fat oxidation, relevant for MASLD research
  • Cardiovascular - improvements across blood pressure, triglycerides, and CRP

Specifications

  • Purity: ≥98% (HPLC & mass spectrometry)
  • Form: Lyophilized powder
  • Storage: 2–8°C after reconstitution, use within 4 weeks
  • CoA: Included

Related: Semaglutide | Tirzepatide

For Research Purposes Only.

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